KCC-07, CAS 315702-75-1

Product Description: KCC-07 is a potent, selective and brain-penetrant MBD2 (methyl-CpG-binding domain protein 2) inhibitor. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling. Anticancer activity[1].

Applications: Cancer-programmed cell death

Formula: C14H11N3OS

References: [1]Dan Zhu, et al. BAI1 Suppresses Medulloblastoma Formation by Protecting p53 From Mdm2-Mediated Degradation. Cancer Cell. 2018 Jun 11;33(6):1004-1016.e5.

CAS Number: 315702-75-1

Molecular Weight: 269.32

Compound Purity: 99.95

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: DNA Alkylator/Crosslinker

• SKU: MEXHY-131031-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-131031-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK