Product Description: KDU691, an imidazopyrazine with potent anti-parasitic activity against blood stage schizonts, gametocytes and liver stages, is a Plasmodium PI4K inhibitor. KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites[1].
Applications: COVID-19-immunoregulation
Formula: C22H18ClN5O2
References: [1]Dembele L, et al. The Plasmodium PI(4)K inhibitor KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites. Sci Rep. 2017;7(1):2325. Published 2017 May 24./[2]Zeeman AM, et al. PI4 Kinase Is a Prophylactic but Not Radical Curative Target in Plasmodium vivax-Type Malaria Parasites. Antimicrob Agents Chemother. 2016;60(5):2858-2863. Published 2016 Apr 22.
CAS Number: 1513879-19-0
Molecular Weight: 419.86
Compound Purity: 99.43
Research Area: Infection
Solubility: DMSO : 150 mg/mL (ultrasonic;warming)
Target: Parasite;PI4K
English
Deutsch
