Kevetrin (hydrochloride), CAS 66592-89-0

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: carbamimidothioic acid, 3-cyanopropyl ester, monohydrochloride

Purity: ≥95%

Formula Markup: C5H9N3S / HCl

Formula Weight: 179.67182

CAS Number: 66592-89-0

Notes: Kevetrin is an activator of p53.{47554,47555} It increases levels of activated p53 and expression of p21 in A549 cells and decreases expression of the transcription factor E2F1 in a variety of cell lines.{47554,47555} Kevetrin decreases cell viability in a panel of cancer cell lines with a mean IC50 value of 0.49 μM.{47556} It reduces tumor growth in MDA-MB-231, HT-29, PC3, HCT15, A549, NCI-H1975, CRL-1619, LNCaP, MIA PaCa, and SCC-5 mouse xenograft models when administered at a dose of 200 mg/kg.

• SKU: CAY28288-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 28288-10
• Package Unit: 10 mg
• Quantity Unit: STK