KIO-301 (chloride) (hydrochloride)

Product Description: KIO-301 chloride hydrochloride is an azobenzene photoswitchable compound that blocks voltage-gated ion channels, including hyperpolarization-activated cyclic nucleotide gating (HCN, during exposure to visible light) ) and voltage-gated potassium channels (voltage-gated potassium channels)[1].

Applications: Neuroscience-Neuromodulation

Formula: C29H39Cl2N5O

References: [1]Eric Daniels, et al. An Intravitreal 'Photoswitch' Molecule (KIO-301) for Reanimation in Retinitis Pigmentosa: a first-in-human trial. Investigative Ophthalmology & Visual Science June 2023, Vol.64, 5444.

Molecular Weight: 544.56

Compound Purity: 99.61

Research Area: Others

Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)

Target: HCN Channel;Potassium Channel

• SKU: MEXHY-161092A-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-161092A-50
• Package Unit: 50 mg
• Quantity Unit: STK