KL001, CAS 309928-48-1

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-[3-(9H-carbazol-9-yl)-2-hydroxypropyl]-N-(2-furanylmethyl)-methanesulfonamide

Purity: ≥98%

Formula Markup: C21H22N2O4S

Formula Weight: 398.5

CAS Number: 309928-48-1

Notes: KL001 is a cryptochrome protein stabilizer.{21468} It inhibits ubiquitin-induced degradation of cryptochrome 1 (CRY1) in HEK293T cells overexpressing CRY1 when used at a concentration of 50 µM. KL001 (0.3-24 µM) lengthens the circadian period in U2OS human osteosarcoma cells in a reporter assay. It reduces glucagon-induced expression of the genes encoding phosphoenolpyruvate carboxykinase (Pck1) and glucose-6-phosphatase (G6pc) in primary mouse hepatocytes in a concentration-dependent manner.

• SKU: CAY13878-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 13878-5
• Package Unit: 5 mg
• Quantity Unit: STK