Klotho blocking peptide

Species: Human

Specificity/Sensitivity: The peptide was used in the production of GTX89443.

Form: Lyophilized powder

Buffer (with preservative): Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservative.

Background: This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq, Jul 2008]

Region Sequence: C-KRDDAKYMYYLKK

Full Name: klotho

• SKU: GTX89443-PEP-100
• Manufacturer: GeneTex
• Manufacturer SKU: GTX89443-PEP-100
• Package Unit: 100 μg
• Quantity Unit: STK
• Human Gene ID: 9365