(KO Validated) PSAP Polyclonal Antibody

(KO Validated) PSAP Polyclonal Antibody
SKU
ELSE-AB-93335-200
Packaging Unit
200μL
Manufacturer
Elabscience Biotechnology

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Target Synonym: PSAP; GLBA; SAP1; prosaposin

Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Background: This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.

Immunogen: Recombinant fusion protein of human PSAP

Dilution: WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW: 58kDa

Observed MW: 63KDa
More Information
SKU ELSE-AB-93335-200
Manufacturer Elabscience Biotechnology
Manufacturer SKU E-AB-93335-200
Package Unit 200μL
Quantity Unit STK
Reactivity Human, Mouse (Murine), Rat (Rattus)
Clonality Polyclonal
Application Western Blotting, Immunohistochemistry
Isotype IgG
Host Rabbit
Conjugate Unconjugated
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