KOTX1, CAS 1788963-83-6

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 3-ethyl-N-(7-fluoro-1,2,3,4-tetrahydro-2-oxo-6-quinolinyl)-4-pyridinecarboxamide

Purity: ≥95%

Formula Markup: C17H16FN3O2

Formula Weight: 313.3

CAS Number: 1788963-83-6

Notes: An ALDH1A3 inhibitor (IC50 = 5.14 nM); potentiates glucose-induced insulin secretion from pancreatic islets isolated from patients with type 2 diabetes at 10 µM; decreases plasma insulin levels and reduces blood glucose levels in an IPGTT in diabetic db/db male mice at 40 mg/kg per day; decreases blood glucose levels and increases plasma insulin levels in a mouse model of high-fat diet-induced obesity at 270 ppm in the diet

• SKU: CAY42249-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42249-10
• Package Unit: 10 mg
• Quantity Unit: STK