KRN5, CAS 1800465-47-7

Product Description: KRN5, a derivative of KRN2, is an oral active Nuclear factor of activated T cells 5 (NFAT5) suppressor, with an IC50 of 750 nM. KRN5 has potential to treat NFAT5-mediated Chronic Arthritis[1].

Applications: COVID-19-immunoregulation

Formula: C27H22FNO5

References: [1]Han EJ, et al. Suppression of NFAT5-mediated Inflammation and Chronic Arthritis by Novel κB-binding Inhibitors. EBioMedicine. 2017 Apr;18:261-273.

CAS Number: 1800465-47-7

Molecular Weight: 459.47

Compound Purity: 98.76

Research Area: Inflammation/Immunology

Solubility: DMSO : 5 mg/mL (ultrasonic;warming;heat to 80°C)

Target: Nuclear Factor of activated T Cells (NFAT)

• SKU: MEXHY-112126-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-112126-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK