Kynurenic acid (Standard), CAS 492-27-3

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Product Description: Kynurenic acid (Standard) is the analytical standard of Kynurenic acid. This product is intended for research and analytical applications. Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8.

Formula: C10H7NO3

References: [1]Wang J, et al. Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35. J Biol Chem. 2006 Aug 4;281(31):22021-8./[2]Albuquerque EX, et al. Kynurenic acid as an antagonist of α7 nicotinic acetylcholine receptors in the brain: facts and challenges. Biochem Pharmacol. 2013 Apr 15;85(8):1027-32./[3]Małaczewska J, et al. Effect of oral administration of kynurenic acid on the activity of the peripheral blood leukocytes in mice. Cent Eur J Immunol. 2014;39(1):6-13.

CAS Number: 492-27-3

Molecular Weight: 189.17

Compound Purity: 98.87

Research Area: Inflammation/Immunology; Neurological Disease; Endocrinology

Solubility: DMSO : 9 mg/mL (ultrasonic;warming)

Target: Apoptosis;CXCR;Endogenous Metabolite;GPR35 ;iGluR

• SKU: MEXHY-100806R-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100806R-100
• Package Unit: 100 mg
• Quantity Unit: STK