Shelf life (days): 1460.0
Formulation: A solid
Formal Name: L-asparagine-2,3,3-d3, monohydrate
Purity: ≥99% deuterated forms (d1-d3)
Formula Markup: C4H5D3N2O3 / H2O
Formula Weight: 153.15146
CAS Number: 2483831-59-8
Notes: L-Asparagine-d3 is intended for use as an internal standard for the quantification of L-asparagine (Item No. 34519) by GC- or LC-MS. L-Asparagine is a non-essential amino acid.{62313} It is formed from L-aspartic acid and L-glutamine (Item No. 23716) by asparagine synthetase (ASNS), and it is deamidated by L-asparaginase to produce L-aspartic acid and ammonia.{62314,62315} L-Asparagine (0.3 mM) reverses ASNS siRNA knockdown-induced decreases in proliferation in a panel of six human cancer cell lines, indicating that both exogenous and endogenous L-asparagine promote proliferation of these cells.{62316} Formulations containing L-asparagine have been used as dietary supplements.