L-p-Bromotetramisole (oxalate), CAS 62284-79-1

L-p-Bromotetramisole (oxalate), CAS 62284-79-1
SKU
CAY18713-5
Packaging Unit
5 mg
Manufacturer
Cayman Chemical

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Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: (6S)-6-(4-bromophenyl)-2,3,5,6-tetrahydro-imidazo[2,1-b]thiazole, monoethanedioate

Purity: ≥98%

Formula Markup: C11H11BrN2S / C2H2O4

Formula Weight: 373.2

CAS Number: 62284-79-1

Notes: Four distinct human isoenzymes of alkaline phosphatase (AP) are known: intestinal (IAP), placental (PLAP), tissue non-specific (NSAP, also known as liver/bone/kidney AP), and germ cell AP (also known as placental-like AP, PLAP-like).{30380} L-p-Bromotetramisole is a cell-permeable inhibitor of all four human AP isoenzymes (Kis =18 and 56 µM for PLAP and NSAP, respectively).{30380,30384,30383,30381} While PLAP is strongly inhibited by L-p-bromotetramisole, a second AP, possibly PLAP-like, shows only partial inhibition.{30383} L-p-Bromotetramisole has been shown to inhibit a tyrosine phosphatase from Drosophila and, as a result, is also used as a tyrosine phosphatase inhibitor.{30382,30385}
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SKU CAY18713-5
Manufacturer Cayman Chemical
Manufacturer SKU 18713-5
Package Unit 5 mg
Quantity Unit STK
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