​​L1Au2, CAS 3038386-42-1

Shelf life (days): 1460

Info: A dual inhibitor of EGFR and TrxR (IC50 = 0.99 µM); inhibits the phosphorylation of EGFR, Akt, and ERK in PC-9 cells at 0.01 or 0.05 µM; inhibits the proliferation of PC-9 and gefitinib-resistant PC-9 cells (IC50s = 0.012 and 1.76 µM, respectively); induces ferroptosis in gefitinib-resistant PC-9 cells; decreases tumor weight and intratumoral Gpx4 levels in a gefitinib-resistant PC-9 mouse xenograft model at 10 mg/kg

Formulation: A solid

Formal Name: [3-[[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-propyn-1-yl](1,3,5-triaza-7-phosphatricyclo[3.3.1.1^3,7]decane-κP⁷)-gold

Purity: ≥95%

Formula Markup: C24H24AuClFN6O2P

Formula Weight: 710.884735

CAS Number: 3038386-42-1

• SKU: CAY43244-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 43244-5
• Package Unit: 5 mg
• Quantity Unit: STK