Laduviglusib trihydrochloride, CAS 1782235-14-6

Description: Laduviglusib trihydrochloride (CT99021 trihydrochloride) is a selective glycogen synthase kinase 3 (GSK-3) inhibitor with IC50s of 10 nM and 6.7 nM for GSK-3α and GSK-3β. Laduviglusib trihydrochloride inhibits human GSK-3β with a Ki of 9.8 nM. Laduviglusib trihydrochloride is an activator of Wnt/β-catenin signaling. Laduviglusib trihydrochloride induces autophagy.

CAS Number: 1782235-14-6

Formula: C22H21Cl5N8

Molecular Weight: 574,72

References: Ring DB, et al. Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes. 2003 Mar;52(3):588-95.

• SKU: TGMT22657-500mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T22657-500mg
• Package Unit: 500 mg
• Quantity Unit: STK