Clone Name: NKTA255
Application Note: FACS: 1/50-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 31
Specificity/Sensitivity: This antibody recognizes human leukocyte-associated Ig-like receptor-1 (LAIR1).
Form: Liquid
Buffer (with preservative): PBS, 0.09% Sodium azide.
Concentration: 1.0 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Uniprot ID: Q6GTX8
Antigen Species: Human
Immunogen: NK cell lines B12.100 and AM.25
Purification: Protein A purified
Conjugation: Unconjugated
Full Name: leukocyte associated immunoglobulin like receptor 1
English
Deutsch
