Product Description: Landiolol hydrochloride (ONO1101 hydrochloride) is a highly beta1 selective ultra-short acting beta-blocker (β1/β2 selectivity = 255:1, a half-life of 4 min), acts as an adrenoceptor antagonist[1].
Applications: COVID-19-immunoregulation
Formula: C25H40ClN3O8
References: [1]Atarashi H, et al. Pharmacokinetics of landiolol hydrochloride, a new ultra-short-acting beta-blocker, in patients with cardiac arrhythmias. Clin Pharmacol Ther. 2000 Aug;68(2):143-50./[2]Okajima M, et al. Landiolol, an ultra-short-acting β1-blocker, is useful for managing supraventricular tachyarrhythmias in sepsis. World J Crit Care Med. 2015 Aug 4;4(3):251-7.
CAS Number: 144481-98-1
Molecular Weight: 546.05
Compound Purity: 99.96
Research Area: Cardiovascular Disease; Endocrinology
Solubility: DMSO : 250 mg/mL (ultrasonic)/H2O : ≥ 100 mg/mL
Target: Adrenergic Receptor