Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 5-(acetylamino)-4-[(aminoiminomethyl)amino]-2,6-anhydro-3,4,5-trideoxy-7-O-methyl-D-glycero-D-galacto-non-2-enonic acid
Purity: ≥98%
Formula Markup: C13H22N4O7
Formula Weight: 346.3
CAS Number: 203120-17-6
Notes: Laninamivir is an inhibitor of influenza neuraminidases and an active metabolite of the prodrug laninamivir octanoate (Item No. 40850).{49847} It inhibits the neuraminidases from influenza A H1N1, H2N2, and H3N2 strains (mean IC50s = 2.49, 11.4, and 16.7 nM, respectively) and influenza B Victoria and Yamagata strains (mean IC50s = 18.9 nM for both). Intranasal administration of laninamivir (69 µg/kg) increases survival in a mouse model of lethal influenza H1N1 infection. Formulations containing laninamivir have been used in the prevention of influenza.