Larazotide (acetate), CAS 881851-50-9

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolyl-glycine, monoacetate salt

Amino Acids: GGVLVQPG

Purity: ≥98%

Formula Markup: C32H55N9O10 / C2H4O2

Formula Weight: 785.897

CAS Number: 881851-50-9

Notes: A peptide antagonist of α3β4 subunit-containing nAChRs; selectively inhibits epibatidine-induced calcium mobilization in HEK293 cells expressing human α3β4 subunit-containing nAChRs over HEK293 cells expressing α4β2 subunit-containing nAChRs (IC50s = 91 and 276 nM, respectively); decreases inflammatory cytokine-induced tight junction dysfunction in isolated rat intestinal epithelial cells at 100 µM; inhibits nicotine self-administration and varenicline-induced reinstatement of nicotine-seeking behavior in rats at 0.3, 3, and 30 µg/kg

• SKU: CAY43008-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 43008-5
• Package Unit: 5 mg
• Quantity Unit: STK