Product Description: Larazotide acetate is a peptide which is an orally active zonulin antagonist. Larazotide acetate shows antiviral activity to varicella-zoster virus (VZV) with EC50s of 44.14 and 59.06 μM for strain OKA and 07-1, respectively. Larazotide acetate can be used for the research of celiac disease and infection.
Applications: COVID-19-immunoregulation
Formula: C34H59N9O12
References: [1]Di Micco S, et al. Peptide Derivatives of the Zonulin Inhibitor Larazotide (AT1001) as Potential Anti SARS-CoV-2: Molecular Modelling, Synthesis and Bioactivity Evaluation. Int J Mol Sci. 2021 Aug 30;22(17):9427./[2]Gopalakrishnan S, et al. Larazotide acetate regulates epithelial tight junctions in vitro and in vivo. Peptides. 2012 May;35(1):86-94.
CAS Number: 881851-50-9
Molecular Weight: 785.89
Compound Purity: 99.74
Research Area: Inflammation/Immunology
Solubility: DMSO : 3.2 mg/mL (ultrasonic;warming)/H2O : 16.67 mg/mL (ultrasonic)
Target: Gap Junction Protein
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