LCS3, CAS 109844-92-0

Description: LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3 μM and 3.8 μM, respectively. LCS3 has antitumour activity, induces apoptosis and can be used in the study of lung adenocarcinoma (LUAD).

CAS Number: 109844-92-0

Formula: C11H7ClN2O4

Molecular Weight: 266,64

References: Johnson FD, et al. Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells. Cell Rep. 2022 ; 38(6):110343.

• SKU: TGMT60446-50mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T60446-50mg
• Package Unit: 50 mg
• Quantity Unit: STK