LDN-192960, CAS 184582-62-5

Product Description: LDN-192960 is an inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50s of 10 nM and 48 nM, respectively[1].

Applications: Cancer-Kinase/protease

Formula: C18H20N2O2S

Citations: Universidad de Córdoba. 2023 Sep 11./Bioorg Chem. 2024 Apr 29:147:107412.

References: [1]Cuny GD, et al. Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3491-4./[2]Katrin Kestav, et al. Structure, Roles and Inhibitors of a Mitotic Protein Kinase Haspin. Curr Med Chem. 2017;24(21):2276-2293.

CAS Number: 184582-62-5

Molecular Weight: 328.43

Compound Purity: 99.56

Research Area: Cancer

Solubility: DMSO : 25 mg/mL (ultrasonic)

Target: DYRK;Haspin Kinase

• SKU: MEXHY-13455-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-13455-100
• Package Unit: 100 mg
• Quantity Unit: STK