Lenalidomide-6-F, CAS 2468780-87-0

Product Description: Lenalidomide-6-F is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-6-F can be connected to the ligand for protein by a linker to form PROTAC[1].

Applications: Cancer-programmed cell death

Formula: C13H11FN2O3

References: [1]Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019;17:160-176. Published 2019 Jan 25./[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

CAS Number: 2468780-87-0

Molecular Weight: 262.24

Compound Purity: 99.63

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Ligands for E3 Ligase

• SKU: MEXHY-138881-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-138881-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK