Lenalidomide-OH, CAS 1416990-08-3

Product Description: Lenalidomide-OH is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein. Lenalidomide-OH can be connected to the ligand for protein by a linker to form PROTACs, such as the PROTAC BTK degrader SJF620 (HY-133137)[1].

Applications: Cancer-programmed cell death

Formula: C13H12N2O4

References: [1]Jaime-Figueroa S, et al. Design, synthesis and biological evaluation of Proteolysis Targeting Chimeras (PROTACs) as a BTK degraders with improved pharmacokinetic properties. 2020 Feb 1;30(3):126877.

CAS Number: 1416990-08-3

Molecular Weight: 260.249

Compound Purity: 99.48

Research Area: Cancer

Solubility: DMSO : 13.89 mg/mL (ultrasonic)

Target: Ligands for E3 Ligase

• SKU: MEXHY-133144-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-133144-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK