Product Description: Letosteine is an orally active, potent and safe expectorant. Letosteine has the effect of scavenging reactive oxygen species (ROS). Letosteine dissolves bronchial mucus and reduces respiratory inflammation symptoms, and restores gas exchanges and natural defense mechanisms in the lung. Letosteine can be used for acute or chronic respiratory diseases (such as bronchopneumopathies) research[1][2][3][4].
Applications: COVID-19-immunoregulation
Formula: C10H17NO4S2
References: [1]Jia L. Letosteine. John Wiley & Sons, Ltd, 2014./[2]Macquet V, et al. A new contribution to the treatment of chronic bronchopneumopathies: letosteine. Lille Med. 1979;24(9):735-738./[3]Zhou Y, et al. Efficacy and safety of letosteine in the treatment of sputum thickening and expectoration difficulty in patients with respiratory diseases: a multicenter, randomized, double-masked, double dummy, positive drug parallel controlled trial. Pharmazie. 2014;69(11):842-849./[4]Gachon F, et al. Disposition and metabolism of letosteine in rats. Drug Metab Dispos. 1988;16(6):853-857./[5]Gressier B, et al. Scavenging of reactive oxygen species by letosteine, a molecule with two blocked-SH groups. Comparison with free-SH drugs. Pharm World Sci. 1995 May 26;17(3):76-80.
CAS Number: 53943-88-7
Molecular Weight: 279.38
Compound Purity: 99.78
Research Area: Inflammation/Immunology
Solubility: DMSO : 11.11 mg/mL (ultrasonic;adjust pH to 12 with 1M NaOH)
Target: Reactive Oxygen Species
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