Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (3S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl-2,2,3,3,5,5,6,6-d8)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, monohydrochloride
Purity: ≥99% deuterated forms (d1-d8)
Formula Markup: C18H12D8FN3O4 / HCl
Formula Weight: 405.876743
CAS Number: 2699607-50-4
Notes: Levofloxacin-d8 is intended for use as an internal standard for the quantification of levofloxacin (Item No. 20382) by GC- or LC-MS. Levofloxacin is a fluoroquinolone antibiotic and the active stereoisomer of ofloxacin (Item No. 22891).{42719} It is active against S. aureus, S. epidermidis, B. subtilis, E. coli, P. aeruginosa, and K. pneumoniae (MICs = 0.25, 0.25, 0.5, 0.03, 4, and 0.25 μg/ml, respectively).{45220} Levofloxacin inhibits S. aureus DNA gyrase and topoisomerase IV (IC50s = 8.06 and 9.81 μg/ml, respectively).{27493} It eliminates infection in rat models of endocarditis caused by methicillin-sensitive or -resistant S. aureus.{42992} Formulations containing levofloxacin have been used in the treatment of various bacterial infections.
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