Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: (2E)-3-[5-(1,1-dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one
Purity: ≥95%
Formula Markup: C21H22O4
Formula Weight: 338.4
CAS Number: 58749-22-7
Notes: Licochalcone A is a natural chalcone first identified in roots and rhizomes of licorice (Glycyrrhiza spp.). It has anti-inflammatory actions, supporting its use as a skin lightening agent, particularly for rosacea and atopic dermatitis.{25888,28180,28177} Licochalcone A (10-50 µM) induces apoptosis and suppresses migration and invasion of cancer cells in vitro.{28176,28179} It also has antibacterial properties against spore-forming bacteria (MIC = 2-15 µg/ml) and anti-parasitic actions (IC50 = 2 µg/ml).{28178,28175}