Product Description: Linarin (Buddleoside) is an orally active and selective inhibitor of acetylcholinesterase (AChE). Linarin has many activities, such as anti-inflammatory, antioxidant, sleep aid and sedation, bone differentiation, anti-tumor, antibacterial and antiviral. Linarin can be used to study diseases such as the nervous system, osteoporosis and cancer[1][2][3][4].
Applications: Neuroscience-Neuromodulation
Formula: C28H32O14
References: [1]Päivi P. Oinonen,etc. Linarin, a selective acetylcholinesterase inhibitor from Mentha arvensis, Fitoterapia,Volume 77, Issue 6, 2006, Pages 429-434, ISSN 0367-326X/[2]Mottaghipisheh J, et al. Linarin, a Glycosylated Flavonoid, with Potential Therapeutic Attributes: A Comprehensive Review. Pharmaceuticals (Basel). 2021 Oct 29;14(11):1104./[3]Singh RP, et al. Acacetin inhibits cell growth and cell cycle progression, and induces apoptosis in human prostate cancer cells: structure-activity relationship with linarin and linarin acetate. Carcinogenesis. 2005 Apr;26(4):845-54./[4]Li J, et al. Linarin promotes osteogenic differentiation by activating the BMP-2/RUNX2 pathway via protein kinase A signaling. Int J Mol Med. 2016 Apr;37(4):901-10.
CAS Number: 480-36-4
Molecular Weight: 592.55
Compound Purity: 98.00
Research Area: Cancer; Infection; Inflammation/Immunology; Neurological Disease
Solubility: DMSO : 250 mg/mL (ultrasonic)
Target: Apoptosis;Bacterial;Cholinesterase (ChE);HIV;Influenza Virus;PKA;TNF Receptor
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