Shelf life (days): 365.0
Formulation: A solution in ethanol
Formal Name: 5S,6R,15S-trihydroxyicosa-7E,9E,11Z,13E-tetraenoic-19,19,20,20,20-d5 acid
Purity: ≥99% deuterated forms (d1-d5)
Formula Markup: C20H27D5O5
Formula Weight: 357.5
CAS Number: 1622429-53-1
Notes: Lipoxin A4-d5 (LXA4-d5) is intended for use as an internal standard for the quantification of LXA4 (Item No. 90410) by GC- or LC-MS. LXA4 is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of 15-HETE or 15-HpETE with human leukocytes.{352} LXA4 is equipotent to leukotriene B4 (LTB4) in inducing superoxide generation in human neutrophils at 0.1 µM.{350} LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis effects, natural killer cell inhibition, and monocyte migration and adhesion.{350,354,2722}
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