Product Description: Lixivaptan (VPA-985, WAY-VPA 985) is an orally active and selective vasopressin receptor V2 antagonist, with IC50 values of 1.2 and 2.3 nM for human and rat V2, respectively.
Applications: COVID-19-immunoregulation
Formula: C27H21ClFN3O2
References: [1]Albright JD, et al. 5-Fluoro-2-methyl-N-[4-(5H-pyrrolo[2,1-c]-[1, 4]benzodiazepin-10(11H)-ylcarbonyl)-3-chlorophenyl]benzamide (VPA-985): an orally active arginine vasopressin antagonist with selectivity for V2 receptors. J Med Chem. 1998 Jul 2;41(14):2442-4./[2]Ghali JK, et al. Lixivaptan, a non-peptide vasopressin V2 receptor antagonist for the potential oral treatment of hyponatremia. IDrugs. 2010 Nov;13(11):782-92.
CAS Number: 168079-32-1
Molecular Weight: 473.93
Compound Purity: 99.30
Research Area: Cardiovascular Disease; Endocrinology
Solubility: DMSO : ≥ 150 mg/mL
Target: Vasopressin Receptor
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