LMT-28, CAS 1239600-18-0

Product Description: LMT-28 is an orally active and the first synthetic IL-6 inhibitor that functions through direct binding to gp130. LMT-28 shows low toxicity and selectively inhibits IL-6-induced phosphorylation of STAT3, JAK2, and gp130[1].

Applications: COVID-19-immunoregulation

Formula: C17H29NO4

References: [1]Hong SS, et al. A Novel Small-Molecule Inhibitor Targeting the IL-6 Receptor β Subunit, Glycoprotein 130. J Immunol. 2015 Jul 1;195(1):237-45.

CAS Number: 1239600-18-0

Molecular Weight: 311.42

Compound Purity: 98.93

Research Area: Inflammation/Immunology

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Interleukin Related

• SKU: MEXHY-102084-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-102084-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK