Product Description: Lorundrostat (MT-4129) is an orally active aldosterone synthase inhibitor. Lorundrostat can be used in studies of high blood pressure[1][2].
Applications: Metabolism-sugar/lipid metabolism
Formula: C24H33N7O2
References: [1]International Nonproprietary Names for Pharmaceutical Substances (INN). WHO Drug Information, Vol. 36, No. 2, 2022./[2]Laffin LJ, et al. Aldosterone Synthase Inhibition With Lorundrostat for Uncontrolled Hypertension: The Target-HTN Randomized Clinical Trial. JAMA. 2023 Sep 26;330(12):1140-1150/[3]Hideki K, et al., Novel disubstituted 1,2,4-triazine compounds. WO2015163427.
CAS Number: 1820940-17-7
Molecular Weight: 451.56
Compound Purity: 99.37
Research Area: Cardiovascular Disease
Solubility: DMSO : 33.33 mg/mL (ultrasonic;adjust pH to 2 with HCl)
Target: Cytochrome P450