Lotilaner, CAS 1369852-71-0

Product Description: Lotilaner is a parasiticide, acts as a potent non-competitive antagonist of insects GABACl receptors, with an IC50 of 23.84 nM for Drosophila melanogaster GABA receptor. No effect on a dog GABAA receptor[1].

Applications: COVID-19-immunoregulation

Formula: C20H14Cl3F6N3O3S

References: [1]Lotilaner, et al. The novel isoxazoline ectoparasiticide lotilaner (Credelio™): a non-competitive antagonist specific to invertebrates γ-aminobutyric acid-gated chloride channels (GABACls). Parasit Vectors. 2017 Nov 1;10(1):530.

CAS Number: 1369852-71-0

Molecular Weight: 596.76

Compound Purity: 99.84

Research Area: Infection

Solubility: DMSO : ≥ 100 mg/mL

Target: GABA Receptor;Parasite

• SKU: MEXHY-116564-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-116564-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK