Shelf life (days): 1460.0
Formulation: A solid
Formal Name: a-methyl-4-[(2-oxocyclopentyl)methyl]-benzeneacetic acid, monosodium salt
Purity: ≥98%
Formula Markup: C15H18O3 / Na
Formula Weight: 269.29139
CAS Number: 80382-23-6
Notes: Loxoprofen is a non-steroidal anti-inflammatory drug (NSAID) and prodrug form of loxoprofen-SRS.{61942} It inhibits COX-1 and COX-2 in isolated human whole blood (IC50s = 6.5 and 13.5 µM, respectively). Loxoprofen reduces acetic acid-induced writhing in mice and carrageenan-induced paw edema and LPS-induced fever in rats (ED30s = 20.1, 0.7, and 2.79 mg/kg, respectively).{1669} Formulations containing loxoprofen have been used in the treatment of pain associated with osteoarthritis, myalgia, and post-traumatic swelling.