LP-533401, CAS 945976-43-2

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-[2-amino-6-[2,2,2-trifluoro-1-(3'-fluoro[1,1'-biphenyl]-4-yl)ethoxy]-4-pyrimidinyl]-L-phenylalanine

Purity: ≥98%

Formula Markup: C27H22F4N4O3

Formula Weight: 526.5

CAS Number: 945976-43-2

Notes: LP-533401 is an inhibitor of tryptophan 5-hydroxylase 1 (Tph1) that blocks the biosynthesis of gut-derived serotonin, completely inhibiting serotonin production in Tph1-expressing cells at a dose of 1 µM.{32686} It prevents the development of and fully rescues, in a dose-dependent manner, osteoporosis in ovariectomized and aged mice.{32686,32684} LP-533401 has also been used to elucidate the role of gut-derived serotonin in pulmonary hypertension and leukemia in mice.{32683,32685}

• SKU: CAY10492-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 10492-25
• Package Unit: 25 mg
• Quantity Unit: STK