LtaS-IN-1, CAS 877950-01-1

Product Description: LtaS-IN-1 (compound 1771) is a potent small-molecule inhibitor of Lipoteichoic acid (LTA) synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology. LtaS-IN-1 alone inhibits Enterococcus.spp 28 strains with varying MIC values ranging from 0.5 μg/mL to 64 μg/mL. LtaS-IN-1 combination with antibiotics abolishs multidrug-resistant E. faecium growth almost completely[1].

Applications: COVID-19-immunoregulation

Formula: C24H17N3O5

References: [1]Paganelli FL, et al. Lipoteichoic acid synthesis inhibition in combination with antibiotics abrogates growth of multidrug-resistant Enterococcus faecium.Int J Antimicrob Agents. 2017 Mar;49(3):355-363.

CAS Number: 877950-01-1

Molecular Weight: 427.41

Compound Purity: 95.05

Research Area: Infection

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Bacterial

• SKU: MEXHY-135813-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-135813-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK