Product Description: LX-3 is a selective activator of the p38 MAPK signaling pathway and activates EGFP reporter genes that are silenced by DNA methylation, such as TNF, EGR1, LY6K, and ISG20[1].
Formula: C20H13BrN4OS
References: [1]Li X, et al., Small molecules capable of activating DNA methylation-repressed genes targeted by the p38 mitogen-activated protein kinase pathway. J Biol Chem. 2018 May 11;293(19):7423-7436.
CAS Number: 380645-50-1
Molecular Weight: 437.31
Research Area: Cancer
Target: p38 MAPK