LX2343, CAS 333745-53-2

Product Description: LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. LX2343 acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 μM. LX2343 stimulates autophagy in its promotion of Aβ clearance.

Applications: Neuroscience-Neurodegeneration

Formula: C22H19ClN2O6S

References: [1]Guo XD, et al. Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid β production and clearance. Acta Pharmacol Sin. 2016 Sep;37(10):1281-1297.

CAS Number: 333745-53-2

Molecular Weight: 474.91

Compound Purity: 99.80

Research Area: Neurological Disease

Solubility: DMSO : ≥ 100 mg/mL

Target: Amyloid-β;Autophagy;Beta-secretase;PI3K

• SKU: MEXHY-111383-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-111383-10.1
• Package Unit: 10mM/1mL
• Quantity Unit: STK