LY-272015, CAS 159730-07-1

Product Description: LY-272015 is an orally active, specific 5-HT2B receptor antagonist. LY-272015 completely inhibits the phosphorylation of ERK2 induced by 5-HT or BW723C86. LY-272015 is antihypertensive in Deoxycorticosterone Acetate (DOCA)-salt-hypertensive rats[1][2].

Formula: C21H24N2O2

References: [1]S W Watts, et al. 5-HT2B-receptor antagonist LY-272015 is antihypertensive in DOCA-salt-hypertensive rats. Am J Physiol. 1999 Mar;276(3):H944-52./[2]Kota Naito, et al. Signal Transduction Mechanism for Serotonin 5-HT2B Receptor-Mediated DNA Synthesis and Proliferation in Primary Cultures of Adult Rat Hepatocytes. Biol Pharm Bull. 2016;39(1):121-9.

CAS Number: 159730-07-1

Molecular Weight: 336.43

Research Area: Cardiovascular Disease

Target: 5-HT Receptor

• SKU: MEXHY-100851-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100851-0
• Package Unit: Get quote
• Quantity Unit: STK