Product Description: LY 278584 is a potent, highly selective 5-HT3 receptor antagonist with a Ki of 1.62 nM. LY 278584 has no activity on 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D, or 5-HT2 receptors[1].
Applications: Neuroscience-Neuromodulation
Formula: C17H22N4O
References: [1]D W Robertson, et al. Synthesis and biochemical evaluation of tritium-labeled 1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-1H-indazole-3-carboxa mide, a useful radioligand for 5HT3 receptors. J Med Chem. 1990 Dec;33(12):3176-81.
CAS Number: 119193-37-2
Molecular Weight: 298.38
Compound Purity: 90.0
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: 5-HT Receptor