Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (ßS)-4-[[5-[(3,4-dihydro-8-methoxy-1(2H)-quinolinyl)methyl]-2-thienyl]methoxy]-ß-1-propyn-1-yl-benzenepropanoic acid
Purity: ≥95%
Formula Markup: C28H29NO4S
Formula Weight: 475.603
CAS Number: 1423018-12-5
Notes: An FFAR1/GPR40 agonist; induces calcium flux in HEK293 cells expressing FFAR1/GPR40 (EC50s = 7, 1, and 3 nM for the human, mouse, and rat receptor, respectively); increases blood levels of GLP-1 in fasted mice at 30 mg/kg; decreases cerebral infarct area in a mouse model of MCAO-induced ischemia-reperfusion injury at 10, 20, or 40 mg/kg