Macozinone (Standard), CAS 1377239-83-2

Product Description: Macozinone (Standard) is the analytical standard of Macozinone. This product is intended for research and analytical applications. Macozinone (PBTZ169) is a bactericidal benzothiazinone and a potent DprE1 (decaprenylphosphoryl-β-d-ribose 2′-oxidase) inhibitor. Macozinone inhibits the essential flavoprotein DprE1 by forming a covalent bond with the active-site Cys387 residue. Macozinone has antituberculosis effect[1][2].

Formula: C20H23F3N4O3S

References: [1][3] Makarov V et al. Towards a new combination therapy for tuberculosis with next generation benzothiazinones. EMBO Mol Med. 2014 Mar;6(3):372-83.

CAS Number: 1377239-83-2

Molecular Weight: 456.48

Research Area: Infection

Target: Antibiotic;Bacterial;Reference Standards

• SKU: MEXHY-12903R-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12903R-5
• Package Unit: 5 mg
• Quantity Unit: STK