MAK683, CAS 1951408-58-4

Product Description: MAK683 is an embryonic ectoderm development (EED) inhibitor extracted from patent US20160176882 A1, compound example 2. MAK683 exhibits IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay[1][2].

Applications: Cancer-programmed cell death

Formula: C20H17FN6O

References: [1]Chan, Ho Man, et al. TRIAZOLOPYRIMIDINE COMPOUNDS AND USES THEREOF. US20160176882 A1./[2]Huang D, et al. Binding Modes of Small-Molecule Inhibitors to the EED Pocket of PRC2. Chemphyschem. 2020 Feb 4;21(3):263-271.

CAS Number: 1951408-58-4

Molecular Weight: 376.39

Compound Purity: 99.26

Research Area: Cancer

Solubility: DMSO : 40 mg/mL (ultrasonic)

Target: Histone Methyltransferase

• SKU: MEXHY-103663-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-103663-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK