Mal((3S,3aR,6S,6aR)-Hexahydrofuro(3,2-b)furan-3,6-diamine-PEG12)-β-Glu-PAB-Exatecan, CAS 3059991-66-8

Product Description: Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB-Exatecan (LP1) is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor Exatecan (HY-13631) and a linker Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB (HY-173635) to make antibody agent conjugate (ADC), AZD0516 (HY-173639)[1].

Applications: Cancer-programmed cell death

Formula: C87H118FN9O34

References: [1]Asurayya WORREDE, et al. Steap2 antibody drug conjugates and uses thereof. WO2024214028A1.

CAS Number: 3059991-66-8

Molecular Weight: 1852.91

Research Area: Cancer

Target: Drug-Linker Conjugates for ADC;Topoisomerase

• SKU: MEXHY-173634-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-173634-0
• Package Unit: Get quote
• Quantity Unit: STK