Product Description: Mal-PEG8-Val-Ala-PAB-SB-743921 (Compound D7) is a Drug-Linker Conjugates for ADC. Mal-PEG8-Val-Ala-PAB-SB-743921 consists of KSP inhibitor SB-743921 (HY-14661) and a linker. Mal-PEG8-Val-Ala-PAB-SB-743921 can be used for synthesis of ADCs[1].
Applications: Cancer-programmed cell death
Formula: C73H96ClN7O19
References: [1]Li Y, et al. A novel antibody-KSP inhibitor conjugate improves KSP inhibitor efficacy in vitro and in vivo. Biomaterials. 2023 Jul 28;301:122258.