Mal-va-mac-SN38, CAS 2778229-31-3

Product Description: Mal-va-mac-SN38 is a drug-linker conjugate for ADC. Mal-va-mac-SN38 contains a ADC cytotoxin SN-38 (HY-13704) and a linker (HY-126364). Mal-va-mac-SN38 can rapidly and covalently bind with endogenous albumin in vivo, resulting in the formation of HSA-va-mac-SN38. Mal-va-mac-SN38 demonstrates exceptional stability in human plasma, and has anti-tumor and anti-metastasis effect[1].

Applications: Cancer-programmed cell death

Formula: C52H61N7O14S

References: [1]Lu Y, et al. Design, synthesis, and biological evaluation of cathepsin B cleavage albumin-binding SN38 prodrug in breast cancer. Bioorg Chem. 2024 Jun;147:107370.

CAS Number: 2778229-31-3

Molecular Weight: 1040.14

Research Area: Cancer

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-159563-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-159563-1
• Package Unit: 1 mg
• Quantity Unit: STK