Mal-VC-PAB-DMEA-PNU-159682, CAS 1178887-17-6

Product Description: Mal-VC-PAB-DMEA-PNU-159682 is a agent-linker conjugate for ADC with potent antitumor activity by using the anti-topoisomerase II agent, PNU-159682, linked via the lysosomally cleavable dipeptide, Mc-VC-PAB. Mal-VC-PAB-DMEA-PNU-159682 can be used in the synthesis of Anti-CD22-NMS249 (HY-164761)[1].

Formula: C66H83N9O22

References: [1]Shang-Fan Yu, et al. A Novel Anti-CD22 Anthracycline-Based Antibody-Drug Conjugate (ADC) That Overcomes Resistance to Auristatin-Based ADCs. Clin Cancer Res. 2015 Jul 15;21(14):3298-306.

CAS Number: 1178887-17-6

Molecular Weight: 1354.41

Research Area: Cancer

Target: Drug-Linker Conjugates for ADC;Topoisomerase

• SKU: MEXHY-171138-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-171138-0
• Package Unit: Get quote
• Quantity Unit: STK