MALT1 inhibitor MI-2, CAS 1047953-91-2

Product Description: MALT1 inhibitor MI-2 is a MALT1 inhibitor (IC50=5.84 μM). MALT1 inhibitor MI-2 binds directly to MALT1, irreversibly suppresses protease function and is accompanied by NF-κB reporter activity suppression, c-REL nuclear localization inhibition, and NF-κB target gene downregulation. MALT1 inhibitor MI-2 shows nontoxic to animals[1].

Applications: Cancer-programmed cell death

Formula: C19H17Cl3N4O3

References: [1]Fontan L, et al. MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo. Cancer Cell. 2012 Dec 11;22(6):812-24.

CAS Number: 1047953-91-2

Molecular Weight: 455.72

Compound Purity: 99.95

Research Area: Cancer

Solubility: DMSO : ≥ 46 mg/mL

Target: MALT1

• SKU: MEXHY-12276-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12276-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK