Product Description: Mc-Pro-PAB-MMAE is a Drug-Linker Conjugate for ADC. Mc-Pro-PAB-MMAE consists of Monomethyl auristatin E (HY-15162) and a linker. Mc-Pro-PAB-MMAE can be used for synthesis of ADCs[1][2].
Formula: C64H95N9O14
References: [1]Ilaria BIANCOFIORE, et al. Fibroblast activation protein ligands for targeted delivery applications. Patent, WO2021160825, 2021-08-19./[2]Bocci M, et al. In vivo activation of FAP-cleavable small molecule-drug conjugates for the targeted delivery of camptothecins and tubulin poisons to the tumor microenvironment[J]. Journal of Controlled Release, 2024, 367: 779-790.
CAS Number: 2766450-03-5
Molecular Weight: 1214.49
Research Area: Cancer
Target: Drug-Linker Conjugates for ADC