Clone Name: MSVA-502R
Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.
Application Note: IHC-P: 1:100 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Form: Liquid
Buffer (with preservative): 10mM PBS, BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format), sodium azide.
Concentration: 66.66 μg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
Uniprot ID: P49736
Antigen Species: Human
Immunogen: Recombinant fragment of human MCM2 protein
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: minichromosome maintenance complex component 2
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