Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: N1,N4-di-2,3-butadien-1-yl-1,4-butanediamine, dihydrochloride
Purity: ≥95%
Formula Markup: C12H20N2 / 2HCl
Formula Weight: 265.2
CAS Number: 93565-01-6
Notes: MDL 72527 is a polyamine oxidase (PAO) inhibitor that inhibits spermine oxidase and N1-acetylpolyamine oxidase (IC50s = 6.1 and 0.02 µM, respectively).{33211} It does not inhibit monoamine oxidase or D-amino acid oxidase. MDL 72527 inhibits PAO-dependent H2O2 production in vitro and in vivo and is used to study the role of PAO activity in diverse models, including infection, cancer, and hyperoxia.{33209,33210,33212}